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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UHRF1
All Species:
13.64
Human Site:
T677
Identified Species:
30
UniProt:
Q96T88
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96T88
NP_001041666.1
793
89814
T677
K
V
E
P
Y
S
L
T
A
Q
Q
S
S
L
I
Chimpanzee
Pan troglodytes
XP_001139655
792
89650
T676
K
V
E
P
Y
S
L
T
A
Q
Q
S
S
L
I
Rhesus Macaque
Macaca mulatta
XP_001082893
795
89906
T679
K
V
E
P
Y
S
L
T
A
Q
Q
S
S
L
I
Dog
Lupus familis
XP_868468
799
89797
T683
K
V
E
P
Y
S
L
T
A
Q
Q
S
S
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDF2
782
88285
E666
A
S
K
K
S
K
L
E
P
Y
T
L
S
E
Q
Rat
Rattus norvegicus
Q7TPK1
774
87430
E658
V
S
K
K
S
K
L
E
P
Y
T
L
P
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507628
851
95788
G735
R
M
A
D
G
G
K
G
G
E
A
F
Q
L
T
Chicken
Gallus gallus
XP_418269
760
84868
K644
A
G
T
P
K
K
T
K
V
E
P
Y
K
L
T
Frog
Xenopus laevis
NP_001129236
772
86955
K656
K
S
I
P
K
K
M
K
V
A
S
Y
K
L
T
Zebra Danio
Brachydanio rerio
NP_998242
775
87072
K658
K
G
T
P
K
K
M
K
V
E
A
Y
K
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791602
653
73619
K538
P
Q
K
P
T
P
K
K
P
K
F
E
L
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.2
88.1
N.A.
74.9
75.7
N.A.
53.3
71.5
66.5
68
N.A.
N.A.
N.A.
N.A.
47.5
Protein Similarity:
100
99.7
98.8
92.7
N.A.
87
87.5
N.A.
68.5
82
79.9
83
N.A.
N.A.
N.A.
N.A.
62.1
P-Site Identity:
100
100
100
100
N.A.
13.3
13.3
N.A.
6.6
13.3
20
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
20
20
N.A.
26.6
20
26.6
33.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
10
0
0
0
0
0
37
10
19
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
37
0
0
0
0
19
0
28
0
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% F
% Gly:
0
19
0
0
10
10
0
10
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
37
% I
% Lys:
55
0
28
19
28
46
19
37
0
10
0
0
28
0
10
% K
% Leu:
0
0
0
0
0
0
55
0
0
0
0
19
10
82
0
% L
% Met:
0
10
0
0
0
0
19
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
73
0
10
0
0
28
0
10
0
10
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
37
37
0
10
0
19
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
28
0
0
19
37
0
0
0
0
10
37
46
10
10
% S
% Thr:
0
0
19
0
10
0
10
37
0
0
19
0
0
0
28
% T
% Val:
10
37
0
0
0
0
0
0
28
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
37
0
0
0
0
19
0
28
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _